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The non-vesicular cholesterol transporter GRAMD1C is a pan-coronavirus antiviral target

The non-vesicular cholesterol transporter GRAMD1C is a pan-coronavirus antiviral target

Published: April 6, 2026 · Plos.org

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Coronaviruses remodel host membranes for replication, but the lipid transport pathways involved are poorly understood. This study identified the cholesterol transporter GRAMD1C as a host factor that promotes replication organelle formation and supports replic…