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The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m6A RNA modification

The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m6A RNA modification

Published: March 24, 2026 · Plos.org

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Gastric cancer (GC) is one of the most common and lethal cancers globally. methyltransferase-like 3 (METTL3)-mediated N6-methyladenosine (m6A) RNA methylation plays a crucial role in tumor initiation and progression by regulating RNA function. STM2457, a high…