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GBP2 promotes podocyte pyroptosis and contributes to the pathogenesis of pediatric lupus nephritis

GBP2 promotes podocyte pyroptosis and contributes to the pathogenesis of pediatric lupus nephritis

Published: March 19, 2026 · Plos.org

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Background Lupus nephritis (LN), a prevalent and serious manifestation of systemic lupus erythematosus, exhibits particularly high incidence in children, yet its pathogenesis remains incompletely elucidated. This study aimed to investigate differentially expr…