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Priming iTBS for lower limb rehabilitation after stroke: Protocol for a randomized controlled trial on efficacy and neuroplasticity

Priming iTBS for lower limb rehabilitation after stroke: Protocol for a randomized controlled trial on efficacy and neuroplasticity

Published: May 21, 2026 · Plos.org

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Introduction Repetitive transcranial magnetic stimulation (rTMS) is widely applied in treating motor dysfunction after stroke. Building on metaplasticity principle, continuous theta burst stimulation (cTBS) preconditioning enhances subsequent excitatory effec…