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Clonorchis sinensis excretory secretory products promote hepatic fibrosis through stimulating biliary epithelium to secrete IL-17A

Clonorchis sinensis excretory secretory products promote hepatic fibrosis through stimulating biliary epithelium to secrete IL-17A

Published: May 5, 2026 · Plos.org

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Author summary C. sinensis excretory and secretory products play critical roles in causing pathological changes of bile duct and periductal liver tissues, yet the mechanism of CsESPs triggering inflammation and fibrosis by breaking the barrier of biliary epit…